Rapid Scale-Up of the Matrix Metalloproteinase Inhibitor CH5902: Process Safety and Route Development Considerations
Author:
Affiliation:
1. Celltech R & D Ltd., Granta Park, Great Abington, Cambridge CB1 6GS, U.K.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op0340762
Reference4 articles.
1. Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors
2. HYDROXYALKANESULFONYL CHLORIDES FROM CHLORINATION OF HYDROXYALKANESULFINATE SALTS IN A NONPOLAR MEDIUM: 3-HYDROXY-1-PROPANESULFONYL AND 4-HYDROXY-1-BUTANESULFONYL CHLORIDES
3. Potential Toxicological Concerns Associated with Carboxylic Acid Chlorination and Other Reactions
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