Scalable and Uniform Fabrication of Dexamethasone-Eluting Depot-Engineered Stem Cell Spheroids as a Microtissue Construct to Target Bone Regeneration

Author:

Nguyen Tiep Tien12,Phuong Mai Thi2,Shrestha Manju3,Park Junhyeung3,Le Minh Pham2,Kim Jong Oh2ORCID,Choi Hyukjae2,Nam Joo-Won2ORCID,Jiang Hu-Lin4567,Kim Hyung-Sik89,Jeong Jee-Heon3ORCID,Park Jun-Beom10,Yook Simmyung1ORCID

Affiliation:

1. College of Pharmacy, Keimyung University, Daegu 42601, Republic of Korea

2. College of Pharmacy, Yeungnam University, Gyeongsan 38541, Gyeongbuk, Republic of Korea

3. Department of Precision Medicine, School of Medicine, Sungkyunkwan University, Suwon 16419, Republic of Korea

4. State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China

5. Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, China Pharmaceutical University, Nanjing 210009, China

6. Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing 210009, China

7. NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparations and Excipients, China Pharmaceutical University, Nanjing 210009, China

8. Department of Life Science in Dentistry, School of Dentistry, Pusan National University, Yangsan 50612, Republic of Korea

9. Dental and Life Science Institute, Pusan National University, Yangsan 50612, Republic of Korea

10. Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea

Funder

Ministry of Health and Welfare

Ministry of Science and ICT, South Korea

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

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