Synthesis and Enzyme-Specific Activation of Carbohydrate−Geldanamycin Conjugates with Potent Anticancer Activity-Reference-Cited by-同舟云学术

Synthesis and Enzyme-Specific Activation of Carbohydrate−Geldanamycin Conjugates with Potent Anticancer Activity

Published:2004-12-31 Issue:2 Volume:48 Page:645-652
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cheng Hao¹,Cao Xianhua¹,Xian Ming¹,Fang Lanyan¹,Cai Tingwei Bill¹,Ji Jacqueline Jia¹,Tunac Josefino B.¹,Sun Duxin¹,Wang Peng George¹

Affiliation:

1. Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, Departments of Biochemistry and Chemistry, The Ohio State University, Columbus, Ohio 43210, and JJ Pharma, Inc., 5000 Executive Plaza, San Ramon, California 94583

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049693a

Reference25 articles.

1. GELDANAMYCIN, A NEW ANTIBIOTIC

2. Crystal Structure of an Hsp90–Geldanamycin Complex: Targeting of a Protein Chaperone by an Antitumor Agent

3. Hsp90 inhibitors as novel cancer chemotherapeutic agents

4. Unusual expression and localization of heat-shock proteins in human tumor cells

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