Comparison of N-Terminal Modifications on Neurotensin(8−13) Analogues Correlates Peptide Stability but Not Binding Affinity with in Vivo Efficacy-Reference-Cited by-同舟云学术

Comparison of N-Terminal Modifications on Neurotensin(8−13) Analogues Correlates Peptide Stability but Not Binding Affinity with in Vivo Efficacy

Published:2009-03-16 Issue:7 Volume:52 Page:1803-1813
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Orwig Kevin S.¹,Lassetter McKensie R.¹,Hadden M. Kyle¹,Dix Thomas A.¹

Affiliation:

1. Department of Pharmaceutical Sciences, Medical University of South Carolina, 280 Calhoun Street, P.O. Box 250140, Charleston, South Carolina 29425, Argolyn Bioscience Inc., 530 Meridian Parkway, Suite 200, Durham, North Carolina 27713

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801072v

Reference81 articles.

1. Optimizing oral absorption of peptides using prodrug strategies

2. Synthesis of 9-fluorenylmethoxycarbonyl-protected amino aldehydes

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