Tubulin Polymerization Promoting Proteins (TPPPs):  Members of a New Family with Distinct Structures and Functions

Author:

Vincze Orsolya1,Tökési Natália1,Oláh Judit1,Hlavanda Emma1,Zotter Ágnes1,Horváth István1,Lehotzky Attila1,Tirián László1,Medzihradszky Katalin F.1,Kovács János1,Orosz Ferenc1,Ovádi Judit1

Affiliation:

1. Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, Budapest, H-1113, Hungary, Department of Biology, Faculty of Medicine, University of Szeged, Szeged, H-6720, Hungary, Department of Pharmaceutical Chemistry, School of Pharmacy, University of CaliforniaSan Francisco, San Francisco, California 94143-0446, and Department of Anatomy, Cell and Developmental Biology, Faculty of Science, Eötvös Loránd University, Budapest, H-1117, Hungary

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Reference30 articles.

1. Hlavanda, E., Kovács, J., Oláh, J., Orosz, F., Medzihradszky, K. F., and Ovádi, J. (2002) Brain-specific p25 protein binds to tubulin and microtubules and induces aberrant microtubule assemblies at substoichiometric concentrations,Biochemistry41, 8657−8664.

2. Dynamic targeting of microtubules by TPPP/p25 affects cell survival

3. Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

4. What does it mean to be natively unfolded?

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