Engineering an Antibiotic to Fight Cancer: Optimization of the Novobiocin Scaffold to Produce Anti-proliferative Agents-Reference-Cited by-同舟云学术

Engineering an Antibiotic to Fight Cancer: Optimization of the Novobiocin Scaffold to Produce Anti-proliferative Agents

Published:2011-05-09 Issue:11 Volume:54 Page:3839-3853
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhao Huiping¹,Donnelly Alison C.¹,Kusuma Bhaskar R.¹,Brandt Gary E. L.¹,Brown Douglas²,Rajewski Roger A.³,Vielhauer George⁴,Holzbeierlein Jeffrey⁴,Cohen Mark S.⁴,Blagg Brian S. J.¹

Affiliation:

1. Department of Medicinal Chemistry, The University of Kansas, 1251 Wescoe Hall Drive, Malott 4070, Lawrence, Kansas 66045-7563, United States

2. Biotechnology Innovation & Optimization Center, The University of Kansas, 2099 Constant Avenue, Lawrence, Kansas 66047-2535, United States

3. Department of Pharmaceutical Chemistry, The University of Kansas, 2095 Constant Avenue, Lawrence, Kansas 66047-2535, United States

4. Department of Urology, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Mail Stop 3016, Kansas City, Kansas 66160, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200148p

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