Synthesis of a Series of 4-Benzyloxyaniline Analogues as Neuronal N-Type Calcium Channel Blockers with Improved Anticonvulsant and Analgesic Properties-Reference-Cited by-同舟云学术

Synthesis of a Series of 4-Benzyloxyaniline Analogues as Neuronal N-Type Calcium Channel Blockers with Improved Anticonvulsant and Analgesic Properties

Published:1999-09-18 Issue:20 Volume:42 Page:4239-4249
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hu Lain-Yen¹,Ryder Todd R.¹,Rafferty Michael F.¹,Feng M. Rose¹,Lotarski Susan M.¹,Rock David M.¹,Sinz Michael¹,Stoehr Sally J.¹,Taylor Charles P.¹,Weber Mark L.¹,Bowersox S. Scott¹,Miljanich George P.¹,Millerman Elizabeth¹,Wang Yong-Xiang¹,Szoke Balazs G.¹

Affiliation:

1. Departments of Chemistry, Neuroscience Therapeutics, and Pharmacokinetics, Dynamics and Metabolism, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan 48105, and Elan Pharmaceuticals, Inc., 3760 Haven Avenue, Menlo Park, California 94025

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9902739

Reference46 articles.

1. (b) Scraibine, A. Calcium channel antagonists as neuroprotective agents.Neuroprot. CNSDis. Baer, P. R., Beal, M. F., Eds.; Dekker: New York, 1997; pp 27−51.

2. Exocytotic Ca2+ channels in mammalian central neurons

3. Antagonists of Neuronal Calcium Channels: Structure, Function, and Therapeutic Implications

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