Conformationally Constrained Analogues of the Muscarinic Agonist 3-(4-(Methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine. Synthesis, Receptor Affinity, and Antinociceptive Activity-Reference-Cited by-同舟云学术

Conformationally Constrained Analogues of the Muscarinic Agonist 3-(4-(Methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine. Synthesis, Receptor Affinity, and Antinociceptive Activity

Published:1998-01-01 Issue:1 Volume:41 Page:109-116
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sauerberg Per¹,Olesen Preben H.¹,Sheardown Malcolm J.¹,Rimvall Karin¹,Thøgersen Henning¹,Shannon Harlan E.¹,Sawyer Barry D.¹,Ward John S.¹,Bymaster Frank P.¹,DeLapp Neil W.¹,Calligaro David O.¹,Swedberg Michael D. B.¹

Affiliation:

1. Health Care Discovery, Novo Nordisk A/S, Novo Nordisk Park, 2760 Måløv, Denmark, and Neuroscience Research, Lilly Research Laboratories, Indianapolis, Indiana 46285

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9705216

Reference26 articles.

1. Antinociceptive effects of intrathecally injected cholinomimetic drugs in the rat and cat

2. A comparison of the antinociceptive actions of cholinomimetic and morphine-like drugs

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