1. Départment de Biologie, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada, Department of Chemistry, Gonda-Goldschmied Center, Bar-Ilan University, Ramat-Gan 52900, Israel, and Institute de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada