Design, Synthesis, and Biological Evaluation of Symmetrically and Unsymmetrically Substituted Methoctramine-Related Polyamines as Muscular Nicotinic Receptor Noncompetitive Antagonists-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Symmetrically and Unsymmetrically Substituted Methoctramine-Related Polyamines as Muscular Nicotinic Receptor Noncompetitive Antagonists

Published:1999-11-23 Issue:25 Volume:42 Page:5212-5223
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rosini Michela¹,Budriesi Roberta¹,Bixel M. Gabriele¹,Bolognesi Maria L.¹,Chiarini Alberto¹,Hucho Ferdinand¹,Krogsgaard-Larsen Povl¹,Mellor Ian R.¹,Minarini Anna¹,Tumiatti Vincenzo¹,Usherwood Peter N. R.¹,Melchiorre Carlo¹

Affiliation:

1. Department of Pharmaceutical Sciences, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy, Institut für Biochemie, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany, Department of Medicinal Chemistry, Royal Danish School of Pharmacy, 2 Universitetsparken, DK 2100 Copenhagen, Denmark, and Division of Molecular Toxicology, School of Biological Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991110n

Reference31 articles.

1. Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors

2. Polymethylene tetramines: a new generation of selective muscarinic antagonists

3. Tetramine disulfides: a new tool in α-adrenergic pharmacology

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