Antitumor Agent Calixarene 0118 Targets Human Galectin-1 as an Allosteric Inhibitor of Carbohydrate Binding-Reference-Cited by-同舟云学术

Antitumor Agent Calixarene 0118 Targets Human Galectin-1 as an Allosteric Inhibitor of Carbohydrate Binding

Published:2012-05-30 Issue:11 Volume:55 Page:5121-5129
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dings Ruud P. M.¹,Miller Michelle C.¹,Nesmelova Irina¹,Astorgues-Xerri Lucile²,Kumar Nigam¹,Serova Maria³,Chen Xuimei⁴,Raymond Eric²,Hoye Thomas R.⁴,Mayo Kevin H.¹

Affiliation:

1. Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota Health Sciences Center, 6-155 Jackson Hall, 321 Church Street, Minneapolis, Minnesota 55455, United States

2. INSERM U728, and Department of Medical Oncology, Beaujon University Hospital (AP-HP−PRES Paris 7 Diderot), 100 bd du Général Leclerc, 92110 Clichy, France

3. AAREC Filia Research, 1 place Paul Verlaine, 92100 Boulogne-Billancourt, France

4. Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300014q

Reference47 articles.

1. Galectins: A family of animal β-galactoside-binding lectins

2. Galectins as modulators of tumour progression

3. Tumour vascular targeting