Structure-Based Design, Synthesis, and Structure−Activity Relationship Studies of Novel Non-nucleoside Adenosine Deaminase Inhibitors-Reference-Cited by-同舟云学术

Structure-Based Design, Synthesis, and Structure−Activity Relationship Studies of Novel Non-nucleoside Adenosine Deaminase Inhibitors

Published:2004-06-17 Issue:15 Volume:47 Page:3730-3743
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Terasaka Tadashi¹,Kinoshita Takayoshi¹,Kuno Masako¹,Seki Nobuo¹,Tanaka Kohichiro¹,Nakanishi Isao¹

Affiliation:

1. Medicinal Chemistry Research Laboratories, Basic Research Laboratories, Medicinal Biology Research Laboratories, and Biopharmaceutical and Pharmacokinetic Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., 2-1-6, Kashima, Yodogawa-ku, Osaka 532-8514, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0306374

Reference35 articles.

1. Adenosine, an endogenous anti-inflammatory agent

2. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

3. Neuroprotective role of adenosine in cerebral ischaemia

4. Adenosine release from stimulated mast cells.

5. Extracellular ATP in T-lymphocyte activation: possible role in effector functions.

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