Cross-Linking and Sequence Specific Alkylation of DNA by Aziridinyl Quinones. 2. Structure Requirements for Sequence Selectivity-Reference-Cited by-同舟云学术

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Cross-Linking and Sequence Specific Alkylation of DNA by Aziridinyl Quinones. 2. Structure Requirements for Sequence Selectivity

Published:1997-01-01 Issue:3 Volume:40 Page:357-361
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hargreaves Rob H. J.¹,Mayalarp Stephen P.¹,Butler John¹,McAdam Simon R.¹,O'Hare C. Caroline¹,Hartley John A.¹

Affiliation:

1. CRC Department of Biophysical Chemistry, Drug Development, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 9BX, U.K., and CRC Drug-DNA Interactions Research Group, Department of Oncology, University College London Medical School, 91 Riding House Street, London W1P 8BT, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960492j

Reference34 articles.

1. Treatment of patients with recurrent primary brain tumors with AZQ

2. Diaziquone (AZQ)

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1. Synthesis of allyl-aziridines from α-halo oxime ethers and allyl zinc bromides;RSC Advances;2016

2. Quenching Enhancement of the Singlet Excited State of Pheophorbide-a by DNA in the Presence of the Quinone Carboquone;Photochemistry and Photobiology;2011-01-04

3. Catalytic asymmetric aziridination of aryl imines;Arkivoc;2007-04-08

4. New Latent Fluorophore for DT Diaphorase;Organic Letters;2005-12-16

5. Diaziridinylbenzoquinones;Methods in Enzymology;2004

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