Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1-Reference-Cited by-同舟云学术

Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1

Published:2015-03-30 Issue:13 Volume:137 Page:4358-4367
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Lee Changwook,Park Hye-Kyung,Jeong Hanbin,Lim Jaehwa,Lee An-Jung,Cheon Keun Young,Kim Chul-Su,Thomas Ajesh P.,Bae Boram,Kim Nam Doo¹,Kim Seong Heon¹,Suh Pann-Ghill,Ryu Ja-Hyoung,Kang Byoung Heon

Affiliation:

1. New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, 701-310, Korea

Funder

Korea Drug Development Fund

Ministry of Health and Welfare

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja511893n

Reference53 articles.

1. HSP90 at the hub of protein homeostasis: emerging mechanistic insights

2. Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers

3. Targeting the dynamic HSP90 complex in cancer

4. HSP90 as a platform for the assembly of more effective cancer chemotherapy

5. Regulation of Tumor Cell Mitochondrial Homeostasis by an Organelle-Specific Hsp90 Chaperone Network

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