Synthesis of Natural Flutimide and Analogous Fully Substituted Pyrazine-2,6-diones, Endonuclease Inhibitors of Influenza Virus-Reference-Cited by-同舟云学术

Synthesis of Natural Flutimide and Analogous Fully Substituted Pyrazine-2,6-diones, Endonuclease Inhibitors of Influenza Virus

Published:2001-07-07 Issue:16 Volume:66 Page:5504-5516
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Singh Sheo B.¹,Tomassini Joanne E.¹

Affiliation:

1. Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, and Department of Antiviral Research, Merck Research Laboratories, West Point, Pennsylvania 19486

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo015665d

Reference19 articles.

1. A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription

2. P1 and P3 proteins of influenza virus are required for complementary RNA synthesis

3. Prophylaxis and Treatment of Influenza

4. (b) Kilbourne, E. D.Influenza, Plenum Press: New York, 1987.

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