Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics-Reference-Cited by-同舟云学术

Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics

Published:2009-11-30 Issue:1 Volume:53 Page:106-118
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gentilucci Luca¹,Cardillo Giuliana¹,Spampinato Santi²,Tolomelli Alessandra¹,Squassabia Federico³,De Marco Rossella¹,Bedini Andrea²,Baiula Monica²,Belvisi Laura⁴,Civera Monica⁴

Affiliation:

1. Department of Chemistry “G. Ciamician”, Università degli Studi di Bologna, via Selmi 2, 40126 Bologna, Italy

2. Department of Pharmacology, Università degli Studi di Bologna, via Irnerio 48, 40126 Bologna, Italy

3. Stepbio srl, Bologna, Via P. Nanni Costa 12/3/e-f, 40133 Bologna, Italy

4. Department of Organic and Industrial Chemistry and CISI, University of Milano, Via Venezian 21, Milano, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9013532

Reference79 articles.

1. Tumor angiogenesis—new drugs on the block

2. Integrin antagonists

3. Requirement of Vascular Integrin α v β 3 for Angiogenesis

4. A reevaluation of integrins as regulators of angiogenesis

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