Decarboxylation Mechanism of <i>iso</i>-Orotate Decarboxylase Revisited-Reference-Cited by-同舟云学术

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Decarboxylation Mechanism of iso-Orotate Decarboxylase Revisited

Published:2024-05-09 Issue:10 Volume:20 Page:4218-4228
ISSN:1549-9618
Container-title:Journal of Chemical Theory and Computation
language:en
Short-container-title:J. Chem. Theory Comput.

Author:

Xiong Jing¹^ORCID,Xu Dingguo²^ORCID

Affiliation:

1. School of Pharmacy, Chengdu Medical College, Chengdu, Sichuan 610500, P. R. China

2. MOE Key Laboratory of Green Chemistry & Technology, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China

Funder

Natural Science Foundation of Sichuan Province

Chengdu Medical College

Fundamental Research Funds for the Central Universities

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jctc.4c00077

Reference36 articles.

1. Active DNA demethylation—The epigenetic gatekeeper of development, immunity, and cancer

2. Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote

3. The Enzymatic Decarboxylation Mechanism of 5-Carboxy Uracil: A Comprehensive Quantum Chemical Study

4. Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase

5. Reaction Mechanism and Substrate Specificity of Iso-orotate Decarboxylase: A Combined Theoretical and Experimental Study

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