Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations
Author:
Affiliation:
1. Janssen Pharmaceuticals, Inc., San Diego, California 92121, United States
Publisher
American Chemical Society (ACS)
Subject
Physical and Theoretical Chemistry,Computer Science Applications
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jctc.9b00483
Reference64 articles.
1. The coming of age of de novo protein design
2. De novo protein design: how do we expand into the universe of possible protein structures?
3. De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy
4. Control over overall shape and size in de novo designed proteins
5. Computational design of ligand-binding proteins with high affinity and selectivity
Cited by 25 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. De novo design of mini-binder proteins against IL-2 receptor β chain;International Journal of Biological Macromolecules;2024-09
2. Enhancing the thermostability of lignin peroxidase: Heme as a keystone cofactor driving stability changes in heme enzymes;Heliyon;2024-09
3. Complex-based Ligand-Binding Proteins Redesign by Equivariant Diffusion-based Generative Models;2024-04-20
4. De novo design of drug-binding proteins with predictable binding energy and specificity;Science;2024-04-05
5. Enhancing the Thermostability of Lignin Peroxidase: Heme as a Keystone Cofactor Driving Stability Changes in Heme Enzymes;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3