Modulation of Amyloid-β42 Conformation by Small Molecules Through Nonspecific Binding-Reference-Cited by-同舟云学术

Modulation of Amyloid-β42 Conformation by Small Molecules Through Nonspecific Binding

Published:2019-09-02 Issue:10 Volume:15 Page:5169-5174
ISSN:1549-9618
Container-title:Journal of Chemical Theory and Computation
language:en
Short-container-title:J. Chem. Theory Comput.

Author:

Liang Chungwen¹^ORCID,Savinov Sergey N.¹²,Fejzo Jasna³,Eyles Stephen J.⁴,Chen Jianhan²⁵^ORCID

Affiliation:

1. Computational Modeling Core Facility, Institute for Applied Life Sciences (IALS), University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States

2. Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States

3. Biomolecular NMR Core Facility, Institute for Applied Life Sciences (IALS), University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States

4. Mass Spectrometry Core Facility, Institute for Applied Life Sciences (IALS), University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States

5. Department of Chemistry, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Physical and Theoretical Chemistry,Computer Science Applications

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jctc.9b00599

Reference58 articles.

1. Alzheimer's Disease and the Amyloid-β Peptide

2. Protein aggregation diseases: pathogenicity and therapeutic perspectives