1. Warshel Institute for Computational Biology, School of Life and Health Sciences, The Chinese University of Hong Kong (Shenzhen), Shenzhen, Guangdong 518172, P. R. China
2. School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China
3. School of Science and Engineering, The Chinese University of Hong Kong (Shenzhen), Shenzhen, Guangdong 518172, P. R. China