Formation of a Quinoneimine Intermediate of 4-Fluoro-N-methylaniline by FMO1: Carbon Oxidation Plus Defluorination-Reference-Cited by-同舟云学术

Formation of a Quinoneimine Intermediate of 4-Fluoro-N-methylaniline by FMO1: Carbon Oxidation Plus Defluorination

Published:2010-04-06 Issue:5 Volume:23 Page:861-863
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Driscoll James P.¹,Aliagas Ignacio¹,Harris Jennifer J.¹,Halladay Jason S.¹,Khatib-Shahidi Sheerin¹,Deese Alan¹,Segraves Nathaniel¹,Khojasteh-Bakht S. Cyrus¹

Affiliation:

1. Departments of Drug Metabolism and Pharmacokinetics, Small Molecule Analytical Chemistry, and Computational Chemistry & Cheminformatics, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx1000688

Reference26 articles.

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