1. Department of Food and Nutrition and Research Institute of Biotechnology, Hungkuang University, 34, Chung-Chie Road, Shalu County, Taichung Hsien, Taiwan 43302, Graduate Institute of Rehabilitation Science, College of Health Care, China Medical University, 91 Hsuen-Shih Road, Taichung, 40202, Taiwan, and Graduate Institute of Bioindustrial Technology, Da-Yeh University, 112, Shan-Jiao Road, Dah-Tsuen, Changhua County, Taiwan 515