Parahydrogen Induced Polarization of 1-13C-Phospholactate-d2 for Biomedical Imaging with >30,000,000-fold NMR Signal Enhancement in Water-Reference-Cited by-同舟云学术

Parahydrogen Induced Polarization of 1-13C-Phospholactate-d2 for Biomedical Imaging with >30,000,000-fold NMR Signal Enhancement in Water

Published:2014-04-16 Issue:12 Volume:86 Page:5601-5605
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Shchepin Roman V.¹,Coffey Aaron M.¹,Waddell Kevin W.¹,Chekmenev Eduard Y.¹

Affiliation:

1. Vanderbilt University Institute of Imaging Science (VUIIS), Department of Radiology, ‡Department of Biomedical Engineering and Biochemistry, §Department of Physics and Astronomy, ∥Department of Biochemistry, ¶Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University, Nashville, Tennessee 37232, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac500952z

Reference37 articles.

1. Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

2. Conversion of a proton pair para order into 13C polarization by rf irradiation, for use in MRI

3. PASADENA hyperpolarization of 13C biomolecules: equipment design and installation

4. Quality assurance of PASADENA hyperpolarization for 13C biomolecules

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