Asymmetric Synthesis of the Highly Potent Anti-Metastatic Prostacyclin Analogue Cicaprost and Its Isomer Isocicaprost-Reference-Cited by-同舟云学术

Asymmetric Synthesis of the Highly Potent Anti-Metastatic Prostacyclin Analogue Cicaprost and Its Isomer Isocicaprost

Published:2003-07-19 Issue:32 Volume:125 Page:9653-9667
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Lerm Marco¹,Gais Hans-Joachim¹,Cheng Kejun¹,Vermeeren Cornelia¹

Affiliation:

1. Contribution from the Institut für Organische Chemie der Rheinisch-Westfälischen Technischen Hochschule (RWTH) Aachen, Prof.-Pirlet-Str. 1, D-52056 Aachen, Germany

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja030200l

Reference97 articles.

1. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

2. Prostacyclin-analogs

3. Synthesis of therapeutically useful prostaglandin and prostacyclin analogs

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