Molecular Modeling on Pyrimidine-Urea Inhibitors of TNF-α Production: An Integrated Approach Using a Combination of Molecular Docking, Classification Techniques, and 3D-QSAR CoMSIA-Reference-Cited by-同舟云学术

Molecular Modeling on Pyrimidine-Urea Inhibitors of TNF-α Production: An Integrated Approach Using a Combination of Molecular Docking, Classification Techniques, and 3D-QSAR CoMSIA

Published:2012-03-15 Issue:3 Volume:52 Page:711-723
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Mouchlis Varnavas D.¹,Melagraki Georgia¹,Mavromoustakos Thomas²,Kollias George³,Afantitis Antreas¹³

Affiliation:

1. Department of Chemoinformatics, NovaMechanics, Ltd., Nicosia, Cyprus

2. Laboratory of Organic Chemistry, Department of Chemistry, University of Athens, Athens 15771, Greece

3. Institute of Immunology, Biomedical Sciences Research Center “Alexander Fleming”, Athens, Greece

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci200579f

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1. Cytokines in the pathogenesis of rheumatoid arthritis

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3. Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases

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