Meriolins (3-(Pyrimidin-4-yl)-7-azaindoles): Synthesis, Kinase Inhibitory Activity, Cellular Effects, and Structure of a CDK2/Cyclin A/Meriolin Complex-Reference-Cited by-同舟云学术

Meriolins (3-(Pyrimidin-4-yl)-7-azaindoles): Synthesis, Kinase Inhibitory Activity, Cellular Effects, and Structure of a CDK2/Cyclin A/Meriolin Complex

Published:2008-01-31 Issue:4 Volume:51 Page:737-751
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Echalier Aude¹,Bettayeb Karima¹,Ferandin Yoan¹,Lozach Olivier¹,Clément Monique¹,Valette Annie¹,Liger François¹,Marquet Bernard¹,Morris Jonathan C.¹,Endicott Jane A.¹,Joseph Benoît¹,Meijer Laurent¹

Affiliation:

1. Laboratory of Molecular Biophysics and Department of Biochemistry, The Rex Richards Building, University of Oxford, South Parks Road, Oxford, OX1 3QU, U.K., C.N.R.S., Cell Cycle Group & UPS2682, Station Biologique, B.P. 74, 29682 Roscoff Cedex, Bretagne, France, Département de Recherches en Cancérologie, Université de Nantes, Inserm U692, 9 Quai Moncousu, 44093 Nantes Cedex 01, France, LBCMCP, UMR-CNRS 5088, IFR 109, Université Paul Sabatier Bat 4R3B1, 118 Route de Narbonne, 31062 Toulouse Cedex, France,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm700940h

Reference88 articles.

1. Mammalian cyclin-dependent kinases

2. The role of CDK5/P25 formation/inhibition in neurodegeneration

3. Cyclin-dependent kinase 5 activity regulates pain signaling

4. Analysis of cyclin B1 and CDK activity during apoptosis induced by camptothecin treatment

5. Cellular control of gene expression by T-type cyclin/CDK9 complexes

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