Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors-Reference-Cited by-同舟云学术

Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors

Published:2014-04-15 Issue:8 Volume:57 Page:3283-3294
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mahajan Sumit S.¹,Scian Michele²,Sripathy Smitha¹,Posakony Jeff¹,Lao Uyen¹,Loe Taylor K.¹,Leko Vid¹,Thalhofer Angel¹,Schuler Aaron D.¹,Bedalov Antonio¹,Simon Julian A.¹³

Affiliation:

1. Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, Washington 98109, United States

2. Department of Medicinal Chemistry, University of Washington, Health Sciences Building, Room H-068, Seattle, Washington 98195, United States

3. Human Biology Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, Washington 98109, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm4018064

Reference31 articles.

1. Antitumor Activity of a Small-Molecule Inhibitor of Human Silent Information Regulator 2 Enzymes

2. Sirtuin Modulators: Mechanisms and Potential Clinical Implications

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