Staurosporine and ent-Staurosporine: The First Total Syntheses, Prospects for a Regioselective Approach, and Activity Profiles1-Reference-Cited by-同舟云学术

Staurosporine and ent-Staurosporine: The First Total Syntheses, Prospects for a Regioselective Approach, and Activity Profiles1

Published:1996-01-01 Issue:12 Volume:118 Page:2825-2842
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Link J. T.¹,Raghavan Subharekha¹,Gallant Michel¹,Danishefsky Samuel J.¹,Chou T. C.¹,Ballas Lawrence M.¹

Affiliation:

1. Contribution from the Department of Chemistry, Columbia University, New York, New York 10027, Laboratory for Bio-Organic Chemistry, and Program for Molecular Pharmacology, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, Department of Chemistry, Yale University, New Haven, Connecticut 06511, and Sphinx Pharmaceuticals, A Division of Eli Lilly and Co., Durham, North Carolina 27707

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja952907g

Reference74 articles.

1. A new alkaloid AM-2282 of Streptomyces origin taxonomy, fermentation, isolation and preliminary characterization.

2. X-Ray crystal structure of staurosporine: a new alkaloid from a Streptomyces strain

3. The Crystal and Molecular Structure of Staurosporine, a New Alkaloid from aStreptomycesStrain

4. A new inhibitor of protein kinase C, RK-286C (4'-demethylamino-4'-hydroxystaurosporine) II. Isolation, physico-chemical properties and structure.

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