Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands-Reference-Cited by-同舟云学术

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Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands

Published:2014-12-16 Issue:2 Volume:6 Page:178-182
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Wallinder Charlotta¹,Sköld Christian¹,Botros Milad²,Guimond Marie-Odile³,Hallberg Mathias²,Gallo-Payet Nicole³,Karlén Anders¹,Alterman Mathias¹

Affiliation:

1. Organic Pharmaceutical Chemistry, Department of Medicinal Chemistry, BMC, Uppsala University, SE-751 23 Uppsala, Sweden

2. Beijer Laboratory, Department of Pharmaceutical Biosciences, BMC, Uppsala University SE-751 23 Uppsala, Sweden

3. Service of Endocrinology, Faculty of Medicine and Heath Sciences, University of Sherbrooke, Sherbrooke J1H 5N4, Quebec, Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml500427r

Reference28 articles.

1. Novel therapeutic targets for the treatment of heart failure

2. Perspective: A tale of two receptors

3. EMA401, an orally administered highly selective angiotensin II type 2 receptor antagonist, as a novel treatment for postherpetic neuralgia: a randomised, double-blind, placebo-controlled phase 2 clinical trial

4. Design, Synthesis, and Biological Evaluation of the First Selective Nonpeptide AT2 Receptor Agonist

5. Selective Angiotensin II AT2 Receptor Agonists: Arylbenzylimidazole Structure−Activity Relationships

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