Effect of the Thymidylate Synthase Inhibitors on dUTP and TTP Pool Levels and the Activities of DNA Repair Glycosylases on Uracil and 5-Fluorouracil in DNA-Reference-Cited by-同舟云学术

Effect of the Thymidylate Synthase Inhibitors on dUTP and TTP Pool Levels and the Activities of DNA Repair Glycosylases on Uracil and 5-Fluorouracil in DNA

Published:2011-01-11 Issue:5 Volume:50 Page:618-627
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Grogan Breeana C.¹,Parker Jared B.¹,Guminski Amy F.¹,Stivers James T.¹

Affiliation:

1. Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205-2185, United States

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi102046h

Reference37 articles.

1. 5-Fluorouracil: mechanisms of action and clinical strategies

2. Participation of DNA repair in the response to 5-fluorouracil

3. Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors

4. ON THE NATURE OF THYMINELESS DEATH

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