A Unified Total Synthesis of the Immunomodulators (−)-Rapamycin and (−)-27-Demethoxyrapamycin: Assembly of the Common C(1−20) Perimeter and Final Elaboration-Reference-Cited by-同舟云学术

A Unified Total Synthesis of the Immunomodulators (−)-Rapamycin and (−)-27-Demethoxyrapamycin: Assembly of the Common C(1−20) Perimeter and Final Elaboration

Published:1997-02-01 Issue:5 Volume:119 Page:962-973
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Smith Amos B.¹,Condon Stephen M.¹,McCauley John A.¹,Leazer Johnnie L.¹,Leahy James W.¹,Maleczka Robert E.¹

Affiliation:

1. Contribution from the Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja963067o

Reference68 articles.

1. Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle.

2. Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.

3. Rapamycin (AY-22,989), a new antifungal antibiotic. III. In vitro and in vivo evaluation.

4. Rapamycin (AY-22,989), a new antifungal antibiotic. IV. Mechanism of action.

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