Disubstituted 1-Aryl-4-Aminopiperidine Library Synthesis Using Computational Drug Design and High-Throughput Batch and Flow Technologies-Reference-Cited by-同舟云学术

Disubstituted 1-Aryl-4-Aminopiperidine Library Synthesis Using Computational Drug Design and High-Throughput Batch and Flow Technologies

Published:2013-08-29 Issue:9 Volume:15 Page:503-511
ISSN:2156-8952
Container-title:ACS Combinatorial Science
language:en
Short-container-title:ACS Comb. Sci.

Author:

Bryan Marian C.¹,Hein Christopher D.¹,Gao Hua¹,Xia Xiaoyang¹,Eastwood Heather¹,Bruenner Bernd A.¹,Louie Steven W.¹,Doherty Elizabeth M.¹

Affiliation:

1. Medicinal Chemistry Research Technologies, ‡Molecular Structure and Characterization, and §Pharmacokinetics and Drug Metabolism, Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/co400078r

Reference26 articles.

1. Application of Combinatorial Chemistry Science on Modern Drug Discovery

2. Microwave and continuous flow technologies in drug discovery

3. Continuous Flow Synthesis. A Pharma Perspective

4. Synthesis of a Drug-Like Focused Library of Trisubstituted Pyrrolidines Using Integrated Flow Chemistry and Batch Methods

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