Design, Synthesis, X-ray Crystallographic Analysis, and Biological Evaluation of Thiazole Derivatives as Potent and Selective Inhibitors of Human Dihydroorotate Dehydrogenase-Reference-Cited by-同舟云学术

Design, Synthesis, X-ray Crystallographic Analysis, and Biological Evaluation of Thiazole Derivatives as Potent and Selective Inhibitors of Human Dihydroorotate Dehydrogenase

Published:2015-01-26 Issue:3 Volume:58 Page:1123-1139
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhu Junsheng¹,Han Le¹,Diao Yanyan¹,Ren Xiaoli¹,Xu Minghao¹,Xu Liuxin¹,Li Shiliang¹,Li Qiang¹,Dong Dong¹,Huang Jin¹,Liu Xiaofeng¹,Zhao Zhenjiang¹,Wang Rui¹,Zhu Lili¹,Xu Yufang¹,Qian Xuhong¹,Li Honglin¹

Affiliation:

1. State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of New Drug Design, and ‡Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

Funder

Natural Science Foundation of Shanghai

Ministry of Education of the People's Republic of China

Ministry of Science and Technology of the People's Republic of China

Shanghai Municipal Education Commission

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Fok Ying Tung Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine