Critical Parameters for Adduct Formation of the Carcinogen (+)-anti-Benzo[a]pyrene-7,8-dihydrodiol 9,10-Epoxide with Oligonucleotides
Author:
Affiliation:
1. Institute of Environmental Medicine, Division of Biochemical Toxicology, Karolinska Institutet, S-17177 Stockholm, Sweden, and Department of Toxicology, University of Mainz, D-55131 Mainz, Germany
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/bc9700188
Reference53 articles.
1. Cheh, A. M., Yagi, H., and Jerina, D. M. (1994) Effect of DNA base sequence on the configuration of deoxyadenosine adducts formed by the fjord region diol epoxide, (+)-(1R,2S,3R,4S)-3,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene.Biochemistry33, 12911−12919.
2. Cosman, M., Ibanez, V., Geacintov, N. E., and Harvey, R. G. (1990) Preparation and isolation of adducts in high yield derived from the binding of two benzo[a]pyrene-7,8-dihydroxy-9,10-oxide stereoisomers to the oligonucleotide d(ATATGTATA).Carcinogenesis (London) 11, 1667−1672.
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