Isothiazolopyridones: Synthesis, Structure, and Biological Activity of a New Class of Antibacterial Agents-Reference-Cited by-同舟云学术

Isothiazolopyridones: Synthesis, Structure, and Biological Activity of a New Class of Antibacterial Agents

Published:2005-12-13 Issue:1 Volume:49 Page:39-42
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wiles Jason A.¹,Hashimoto Akihiro¹,Thanassi Jane A.¹,Cheng Jijun¹,Incarvito Christopher D.¹,Deshpande Milind¹,Pucci Michael J.¹,Bradbury Barton J.¹

Affiliation:

1. Achillion Pharmaceuticals, Inc., 300 George Street, New Haven, Connecticut 06511-6653, and X-ray Crystallographic Facility, Department of Chemistry, Yale University, P.O. Box 208107, New Haven, Connecticut 06520-8107

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm051066d

Reference29 articles.

1. Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

2. Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

3. Mechanism of DNA cleavage and substrate recognition by a bovine apurinic endonuclease

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