Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats-Reference-Cited by-同舟云学术

Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats

Published:2009-03-23 Issue:8 Volume:52 Page:2587-2602
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shen Hong C.¹,Ding Fa-Xiang¹,Deng Qiaolin¹,Wilsie Larissa C.¹,Krsmanovic Mihajlo L.¹,Taggart Andrew K.¹,Carballo-Jane Ester¹,Ren Ning¹,Cai Tian-Quan¹,Wu Tsuei-Ju¹,Wu Kenneth K.¹,Cheng Kang¹,Chen Qing¹,Wolff Michael S.¹,Tong Xinchun¹,Holt Tom G.¹,Waters M. Gerard¹,Hammond Milton L.¹,Tata James R.¹,Colletti Steven L.¹

Affiliation:

1. Departments of Medicinal Chemistry, Cardiovascular Diseases, Pharmacology, and Drug Metabolism, Merck Research Laboratories, Merck & Co., Inc., Rahway, New Jersey 07065-0900

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900151e

Reference65 articles.

1. Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review

2. Drug Treatment of Lipid Disorders

3. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia

4. One-year reduction and longitudinal analysis of carotid intima-media thickness associated with colestipol/niacin therapy.

5. Prevention of progression of coronary atherosclerosis by treatment of hyperlipidaemia: a seven year prospective angiographic study.

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