Diastereofacial Selective Addition of Ethynylcerium Reagent and Barton−McCombie Reaction as the Key Steps for the Synthesis of C-3‘-Ethynylribonucleosides and of C-3‘-Ethynyl-2‘-deoxyribonucleosides

Author:

Jung Pierre M. J.1,Burger Alain1,Biellmann Jean-François1

Affiliation:

1. Laboratoire de Chimie Organique Biologique URA 31 du CNRS, Faculté de Chimie, Université Louis Pasteur, 1 rue Blaise Pascal, 67008 Strasbourg Cedex, France

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference39 articles.

1. For reviews, see for instance:  (a) Périgaud C.; Gosselin G.; Imbach J.L.Nucleosides Nucleotides1992,11, 903−945. (b) Herdewijn P.; Balzarini J.; De Clercq E. InAdvances in Antiviral Drug Design; De Clercq E., Ed. JAI Press, Inc.  Greenwich, 1993; Vol. 1, pp 233−309.

2. An Example of Alkyne-Alkyne Interaction

3. Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogs

4. Epimerization during the acetolysis of 3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-3-C-methyl-α-d-ribofuranose. Synthesis of 3′-C-methylnucleosides with the β-d-ribo- and α-d-arabino configurations

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