Monitoring of Biological One-Electron Reduction by 19F NMR Using Hypoxia Selective Activation of an 19F-Labeled Indolequinone Derivative-Reference-Cited by-同舟云学术

Monitoring of Biological One-Electron Reduction by 19F NMR Using Hypoxia Selective Activation of an 19F-Labeled Indolequinone Derivative

Published:2009-10-20 Issue:44 Volume:131 Page:15982-15983
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Tanabe Kazuhito¹,Harada Hiroshi¹,Narazaki Michiko¹,Tanaka Kazuo¹,Inafuku Kenichi¹,Komatsu Hirokazu¹,Ito Takeo¹,Yamada Hisatsugu¹,Chujo Yoshiki¹,Matsuda Tetsuya¹,Hiraoka Masahiro¹,Nishimoto Sei-ichi¹

Affiliation:

1. Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University, Katsura Campus, Nishikyo-ku, Kyoto 615-8510, Japan, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan, Nano-Medicine Merger Education Unit, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan, Department of Systems Science, Graduate School of Informatics, Kyoto University, Yoshida-Honmachi, Sakyo-ku,...

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja904953b

Reference30 articles.

1. Design of anticancer prodrugs for reductive activation

2. Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential

3. Current molecular design of intelligent drugs and imaging probes targeting tumor-specific microenvironments

4. Tumor hypoxia: A target for selective cancer therapy

5. Hypoxia — a key regulatory factor in tumour growth

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