Anticancer Activity from Gold-alpha-Lactalbumin Nanoconstructs?
Author:
Affiliation:
1. Ugelstad Laboratory, Department of Chemical Engineering, Norwegian University of Science and Technology (NTNU), N-7491 Trondheim, Norway
2. Department of Molecular Biology, University of Bergen, Thormøhlensgt 55 90, 5008 Bergen, Norway
Publisher
American Chemical Society (ACS)
Subject
Surfaces, Coatings and Films,Physical and Theoretical Chemistry,General Energy,Electronic, Optical and Magnetic Materials
Link
https://pubs.acs.org/doi/pdf/10.1021/jp3104886
Reference45 articles.
1. α-Lactalbumin binding and membrane integrity—effect of charge and degree of unsaturation of glycerophospholipids
2. α-Lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human α-lactalbumin made lethal to tumor cells)
3. Conversion of alpha -lactalbumin to a protein inducing apoptosis
4. Molecular Characterization of α–Lactalbumin Folding Variants That Induce Apoptosis in Tumor Cells
5. HAMLET Interacts with Lipid Membranes and Perturbs Their Structure and Integrity
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