1. Departments of Pharmaceutical Molecular Biology and Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan, Mitsubishi Kagaku Institute of Life Sciences, Minamiooya, Machida, Tokyo 194-8511, Japan, Laboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo 192-0392, Japan, and Department of Pharmacology and Physiology, University of Rochester Medical Center, 601 Elmwood...