Crystallographic Snapshots of Nonaged and Aged Conjugates of Soman with Acetylcholinesterase, and of a Ternary Complex of the Aged Conjugate with Pralidoxime-Reference-Cited by-同舟云学术

Crystallographic Snapshots of Nonaged and Aged Conjugates of Soman with Acetylcholinesterase, and of a Ternary Complex of the Aged Conjugate with Pralidoxime

Published:2009-07-30 Issue:23 Volume:52 Page:7593-7603
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sanson Benoît¹,Nachon Florian²,Colletier Jacques-Philippe¹,Froment Marie-Thérèse²,Toker Lilly³,Greenblatt Harry M.⁴,Sussman Joel L.⁴,Ashani Yaacov³,Masson Patrick¹²,Silman Israel³,Weik Martin¹

Affiliation:

1. Laboratoire de Biophysique Moléculaire, Institut de Biologie Structurale Jean-Pierre Ebel, Commissariat à l’Énergie Atomique, Centre National de la Recherche Scientifique, Université Joseph Fourier, 41 Rue Jules Horowitz, 38027 Grenoble, France

2. Département de Toxicologie, Centre de Recherches du Service de Santé des Armées, 24 Avenue des Maquis du Grésivaudan, 38700 La Tronche, France

3. Department of Neurobiology

4. Department of Structural Biology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900433t

Reference82 articles.

1. Acetylcholinesterase: ‘classical’ and ‘non-classical’ functions and pharmacology

2. Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein