Influence of Nano-Carrier Architecture on in Vitro siRNA Delivery Performance and in Vivo Biodistribution: Polyplexes vs Micelleplexes

Author:

Gary Dana J.1,Lee Hoyoung1,Sharma Rahul1,Lee Jae-Sung1,Kim Youngwook2,Cui Zheng Yun2,Jia Di3,Bowman Valorie D.3,Chipman Paul R.3,Wan Lei4,Zou Yi4,Mao Guangzhao4,Park Keunchil25,Herbert Brittney-Shea6,Konieczny Stephen F.3,Won You-Yeon1

Affiliation:

1. School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States

2. Medical Nanoelement Development Center, Samsung Medical Center, Seoul, Korea 135-710

3. Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, United States

4. Department of Chemical Engineering and Materials Science, Wayne State University, Detroit, Michigan 48202, United States

5. Department of Hematology and Oncology, Samsung Medical Center, Seoul, Korea 135-710

6. Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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