Stable Expression of Rat Dihydrodiol Dehydrogenase (AKR1C9) in Human Breast MCF-7 Cells Results in the Formation of PAH-o-Quinones and Enzyme Mediated Cell Death-Reference-Cited by-同舟云学术

Stable Expression of Rat Dihydrodiol Dehydrogenase (AKR1C9) in Human Breast MCF-7 Cells Results in the Formation of PAH-o-Quinones and Enzyme Mediated Cell Death

Published:2001-06-20 Issue:7 Volume:14 Page:856-862
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Tsuruda Laurie¹,Hou Yong-tai¹,Penning Trevor M.¹

Affiliation:

1. Department of Pharmacology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6084

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx0100035

Reference30 articles.

1. Benzo[a]pyrene-nucleic acid derivative found in vivo: structure of a benzo[a]pyrenetetrahydrodiol epoxide-guanosine adduct

2. Generation of Reactive Oxygen Species during the Enzymatic Oxidation of Polycyclic Aromatic Hydrocarbon trans-Dihydrodiols Catalyzed by Dihydrodiol Dehydrogenase

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