Provisional Classification and in Silico Study of Biopharmaceutical System Based on Caco-2 Cell Permeability and Dose Number

Author:

Pham-The Hai1,Garrigues Teresa2,Bermejo Marival3,González-Álvarez Isabel3,Monteagudo Maikel Cruz456,Cabrera-Pérez Miguel Ángel123

Affiliation:

1. Molecular Simulation & Drug Design Group, Centre of Chemical Bioactive, Central University of Las Villas, Santa Clara 54830, Villa Clara, Cuba

2. Department of Pharmacy and Pharmaceutical Technology, University of Valencia, Burjassot 46100, Valencia, Spain

3. Department of Engineering, Area of Pharmacy and Pharmaceutical Technology, Miguel Hernández University, 03550 Sant Joan d’Alacant, Alicante, Spain

4. CIQ, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal

5. REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal

6. Applied Chemistry Research Center (CEQA), Faculty of Chemistry and Pharmacy, Central University of Las Villas, Santa Clara, 54830, Cuba

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference68 articles.

1. The BCS, BDDCS, and Regulatory Guidances

2. Annex 8: Proposal to waive in vivo bioequivalence requirements for WHO Model List of Essential Medicines immediate-release, solid oral dosage forms; Technical Report Series No. 937; 40th; WHO Expert Committee on Specification for Pharmaceutical Preparations, WHO Technical Report Series, No. 937, 2006; pp391–461;http://www.who.int/medicines/publications/essentialmedicines/en/index.html(accessed March 3, 2012) .

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