Synthesis and Structure−Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase-Reference-Cited by-同舟云学术

Synthesis and Structure−Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase

Published:2011-04-05 Issue:8 Volume:54 Page:3037-3050
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hwang Sung Hee¹,Wagner Karen M.¹,Morisseau Christophe¹,Liu Jun-Yan¹,Dong Hua¹,Wecksler Aaron T.¹,Hammock Bruce D.¹

Affiliation:

1. Department of Entomology and Cancer Center, University of California, One Shields Avenue, Davis, California 95616-8584, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2001376

Reference58 articles.

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4. Prevention of thrombosis and vascular inflammation: benefits and limitations of selective or combined COX-1, COX-2 and 5-LOX inhibitors

5. Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression

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