Discovery of γ-Lactam Hydroxamic Acids as Selective Inhibitors of Tumor Necrosis Factor α Converting Enzyme: Design, Synthesis, and Structure−Activity Relationships-Reference-Cited by-同舟云学术

Discovery of γ-Lactam Hydroxamic Acids as Selective Inhibitors of Tumor Necrosis Factor α Converting Enzyme: Design, Synthesis, and Structure−Activity Relationships

Published:2002-10-15 Issue:23 Volume:45 Page:4954-4957
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Duan James J.-W.¹,Chen Lihua¹,Wasserman Zelda R.¹,Lu Zhonghui¹,Liu Rui-Qin¹,Covington Maryanne B.¹,Qian Mingxin¹,Hardman Karl D.¹,Magolda Ronald L.¹,Newton Robert C.¹,Christ David D.¹,Wexler Ruth R.¹,Decicco Carl P.¹

Affiliation:

1. Discovery Chemistry, Bristol-Myers Squibb Company, Experimental Station, Wilmington, Delaware 19880-0500

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0255670

Reference22 articles.

1. Therapeutic Potential and Strategies for Inhibiting Tumor Necrosis Factor-α

2. Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

3. Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis

4. A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

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