Type-II Kinase Inhibitor Docking, Screening, and Profiling Using Modified Structures of Active Kinase States
Author:
Affiliation:
1. The Scripps Research Institute, La Jolla, CA, and Molsoft, LLC, La Jolla, CA
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm8010299
Reference49 articles.
1. The Protein Kinase Complement of the Human Genome
2. Protein kinases — the major drug targets of the twenty-first century?
3. A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding
4. Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
5. Design and Discovery of Small Molecules Targeting Raf-1 Kinase
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