Assessment of the Radiochemical Design of Antibodies with a Metabolizable Linkage for Target-Selective Radioactivity Delivery-Reference-Cited by-同舟云学术

Assessment of the Radiochemical Design of Antibodies with a Metabolizable Linkage for Target-Selective Radioactivity Delivery

Published:1998-06-19 Issue:4 Volume:9 Page:497-506
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Arano Yasushi¹,Wakisaka Kouji¹,Akizawa Hiromichi¹,Ono Masahiro¹,Kawai Keiichi¹,Nakayama Morio¹,Sakahara Harumi¹,Konishi Junji¹,Saji Hideo¹

Affiliation:

1. Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, and Department of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine, Kyoto University, Yoshida-Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Central Research Laboratories, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, Miyazaki-gun 889-1601, and Faculty of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-Honmachi, Kumamoto 862-0973, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc970220a

Reference44 articles.

1. Metabolizable 111in chelate conjugated anti-idiotype monoclonal antibody for radioimmunodetection of lymphoma in mice

2. Faivre-Chauvet, A., Gestin, J. F., Mease, R. C., Sai-Maurel, C., Thedrez, P., Slinkin, M., Meinken, G. E., Srivastava, S. C., and Chatal, J. F. (1993) Introduction of Five Potentially Metabolizable Linking Groups Between In-111-Cyclohexyl EDTA Derivatives and F(ab‘)2Fragments of Anti-Carcinoembryonic Antigen Antibody. 2. Comparative Pharmacokinetics and Biodistribution in Human Colorectal Carcinoma-Bearing Nude Mice.Nucl. Med. Biol.20, 763−771.

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