Discovery of a Novel Binding Trench in HIV Integrase
Author:
Affiliation:
1. Department of Pharmacology and Department of Chemistry and Biochemistry, Howard Hughes Medical Institute, University of California, San Diego, La Jolla, California 92093-0365
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0341913
Reference10 articles.
1. Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drug design
2. HIV-1 Integrase Inhibitor Interactions at the Active Site: Prediction of Binding Modes Unaffected by Crystal Packing
3. Molecular Dynamics Studies of the Wild-Type and Double Mutant HIV-1 Integrase Complexed with the 5CITEP Inhibitor: Mechanism for Inhibition and Drug Resistance
4. Varmus, H.; Coffin, J. M.; Hughes, S. H.Retroviruses; Cold Spring Harbor Laboratory Press: Plainview, NY, 1997.
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