Structure−Activity Relationship of Imidazo[1,2-a]pyridines as Ligands for Detecting β-Amyloid Plaques in the Brain-Reference-Cited by-同舟云学术

Structure−Activity Relationship of Imidazo[1,2-a]pyridines as Ligands for Detecting β-Amyloid Plaques in the Brain

Published:2002-12-18 Issue:2 Volume:46 Page:237-243
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhuang Zhi-Ping¹,Kung Mei-Ping¹,Wilson Alan¹,Lee Chi-Wan¹,Plössl Karl¹,Hou Catherine¹,Holtzman David M.¹,Kung Hank F.¹

Affiliation:

1. Departments of Radiology and Pharmacology, University of Pennsylvania, 3700 Market Street, Room 305, Philadelphia, Pennsylvania 19104, Department of Psychiatry, University of Toronto, PET Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8, and Departments of Neurology, Molecular Biology and Pharmacology, Washington University, St. Louis, Missouri 63110

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020351j

Reference30 articles.

1. Alzheimer's Disease: Genes, Proteins, and Therapy

2. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

3. The Origins of Alzheimer Disease

4. X-34, A Fluorescent Derivative of Congo Red: A Novel Histochemical Stain for Alzheimer's Disease Pathology

5. In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease

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